Books/Autonomic nervous system/Receptors
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| Autonomic Nervous System |
In the transmission of nerve impulse, continuous conduction of electrical signal is required and this done by neurochemicals by acting on receptors, which are either voltage gated or chemical, mediated. These receptors are located on heads or tails of neuron called dendron or on effecter organ like muscles etc. The drug receptor interaction is a signal transmission phenomenon, could follow any of the following mechanisms for adrenergic and cholinergic agonist and antagonist:-
1. Receptor linked to ion channels (ligand gated or voltage gated receptors)
2. Receptor controlled generation of second messenger (G-protein linked with c AMP or G protein linked with phosphoinositide systems).
 This is a free Pharmpedia textbookAuthor Prof.A.N.Nagappa |
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