Courses:Pulmonary Drug Delivery/Definition
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< Courses:Pulmonary Drug Delivery
1. What is an Aerosol?
Aerosol is a pressure package or pressurized package. It can be defined as a “system that depends on the power of a compressed or liquefied gas to expel the contents from the container”.
Certain gases under pressure liquefy while some gases are not capable of being liquefied. Both these types of gases serve as medium in which the drug is uniformly dispersed to form the product. The product is packaged under high pressure in a container. The aerosol product container has provision of being opened and closed easily. When it is opened, it releases the product into the atmosphere, where the liquefied or compressed gas goes back into the gaseous phase dispersing the product into fine particles, the size of which is determined by the type and concentration of the gas used in the product.
Aerosols have been used for both topical as well as oral inhalation aerosols for pulmonary delivery of drugs such as bronchodilators and steroids. Topical products are used for treatment of burns, minor cuts, bruises and infections.
Some of the products in India are;
1.Beclate Inhaler by CIPLA containing 50 µg Beclomethasone dipropionate as the active ingredient.
2.Beclate Rotocaps by CIPLA contains 100 µg Beclomethasone dipropionate.
3.Asthalin Inhaler by CIPLA contains 100 µg Salbutamol
4.Aerocort Inhaler CIPLA- Salbutamol 100 µg & Beclomethasone dipropionate 50 µg
5.Budecort 200 Inhaler CIPLA- Budesonide 200 µg suspended in Prop HFA 134 a
6.Bricaryl Inhaler Astra- Terbutaline sulphate 250 µg
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