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Delayed action tablets

From Pharmpedia

Delayed action and Enteric coated tablets They are tablets with a coating that resist dissolution or disruption in the gastric fluid (stomach) but readily disintegrate in the intestinal fluid to release the drug, thus rendering them delayed release features. Enteric coating is generally employed when the drug substance is unstable in gastric fluid and may get destroyed or where it may cause irritation to the gastric mucosa or in cases where the bypassing the stomach would result in the enhancement of drug absorption from the intestine to a significant extent. The coating materials are primarily mixed with acid functionality and acid ester functionally synthetic or modified natural polymers. Cellulose acetate phthalate (CAP) is the most commonly used enteric coating polymer. Other materials are polyvinyl acetate phthalate (PVAP) and hydoxy propyl methyl cellulose phthalate (HPMCP).

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This page has been accessed 434 times. This page was last modified 15:00, 7 August 2006. All content, except where otherwise noted, is licensed under a Creative Commons Attribution License.

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