General Principles Of Pharmacology/Agonistic mechanisms
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Antagonists
• Drug serves as a precursor: L-DOPA - Dopamine
• Drug stimulates the release of neurotransmitter: Black Widow Spider Vemon - ACh
• Drug blocks autoreceptor, increasing synthesis or release of neurotransmitter: Clonidine - Norepinephrine
• Drug stimulates postsynaptic receptors: Nicotine or Muscarine - ACh
• Drug blocks reuptake by blocking transporters: Cocaine - Dopamine
• Drug inactivates acetylcholineesterase: Physotigmine - ACh
Next Page: Antagonistic Mechanisms
Previous Page: Drug-Receptor Affinity: Agonists and
Antagonists
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