General Principles Of Pharmacology:Contents
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Chapter 1
- Introduction:Pharmacology and its Branches
- Passive Diffusion
- Facilitated Diffusion
- Active Transport
- Pinocytosis
- How do the molecules cross the cell membrane?
- Drug Distribution And Other Factors
- Passage of drug into the CNS
- Passage of drug into the Placenta
- Drug Dilution in Body Water
- Sites of Drug Binding and its Effect on Drug Distribution
- Drug metabolism: some definitions and explanatory notes their glomerular filtration
- Drug Transformation and Clinical Considerations
- Individual Differences
- Age and Sex Differences
- Drug Transformation and Drug-Drug Interactions
- Drug Transformation of Endogenous Compounds
- Drug Transformation in Diseases and Drug Metabolism
- Drug Transformation and Toxic Products
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Chapter 2
- Pharmacodynamics
- Cells of the CNS
- Neurotransmitters
- The Synapse
- Drug-Receptor Affinity: Agonists and Antagonists
- Agonistic Mechanisms
- Antagonistic Mechanisms
- Sites of Drug Action: Drugs and Receptors
- Disease Processes
- Concept of specific drug receptors
- Types of Receptors
- Drug Therapy
- Binding and Response
- Molecular Aspects of Binding
- Measurement of Effect
- Analysis of Effect
- Occupation Theories
- Responses in the Patient
- Responses in a Population
- Therapeutic Index
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Chapter 3
- Pharmacokinetics
- Three Basic Concepts
- First Order Model
- Multiple Dose Kinetics
- Renal Extraction Ratio
- Drug Excretion:Mechanisms of Renal Excretion
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