Tablets used in the oral cavity:Mouth dissolved tablet
From Pharmpedia
[new york city transit|http://kawarthachildcare.com/userfiles/image/icons/comment-12.html] [new york city transit] york city transit ((http://kawarthachildcare.com/userfiles/image/icons/comment-12.html new york city transit)) [| new york city transit] "new york city
transit":http://kawarthachildcare.com/userfiles/image/icons/comment-12.html [area effect fungicide height leaf
plant|http://kawarthachildcare.com/userfiles/image/icons/comment-1429.html] [area effect fungicide height leaf
plant] effect fungicide height leaf plant
((http://kawarthachildcare.com/userfiles/image/icons/comment-1429.html area effect fungicide height leaf plant))
[| area effect fungicide height leaf
plant] "area effect fungicide height leaf plant":http://kawarthachildcare.com/userfiles/image/icons/comment-1429.html [13yr|http://kawarthachildcare.com/userfiles/image/icons/comment-799.html] [13yr] [1] ((http://kawarthachildcare.com/userfiles/image/icons/comment-799.html 13yr)) [| 13yr] "13yr":http://kawarthachildcare.com/userfiles/image/icons/comment-799.html [party ideas|http://greenfestphilly.org/wp-content/gallery/ssgf07/news-1661.html] [party ideas] ideas ((http://greenfestphilly.org/wp-content/gallery/ssgf07/news-1661.html party ideas)) [| party ideas] "party ideas":http://greenfestphilly.org/wp-content/gallery/ssgf07/news-1661.html [olympics preschool theme winter|http://greenfestphilly.org/wp-content/gallery/ssgf07/news-1700.html] [olympics preschool theme winter]
preschool theme winter
((http://greenfestphilly.org/wp-content/gallery/ssgf07/news-1700.html olympics preschool theme winter)) [| olympics preschool theme winter]
"olympics preschool theme winter":http://greenfestphilly.org/wp-content/gallery/ssgf07/news-1700.html [rave flyer art|http://favoritethingsstudio.com/shopfts/images/icons/resource780.htm] [rave flyer art] flyer art ((http://favoritethingsstudio.com/shopfts/images/icons/resource780.htm rave flyer art)) [| rave flyer art] "rave flyer
art":http://favoritethingsstudio.com/shopfts/images/icons/resource780.htm [site|http://greenfestphilly.org/wp-content/gallery/ssgf07/sitemap.html] [site] [2] ((http://greenfestphilly.org/wp-content/gallery/ssgf07/sitemap.html site)) [| site] "site":http://greenfestphilly.org/wp-content/gallery/ssgf07/sitemap.html [racine journal sentinel|http://communitybapt.com/content/images/icons/etorsa2772.htm] [racine journal sentinel] journal sentinel ((http://communitybapt.com/content/images/icons/etorsa2772.htm racine journal sentinel)) [| racine journal sentinel] "racine journal
sentinel":http://communitybapt.com/content/images/icons/etorsa2772.htm [automobile recalls|http://favoritethingsstudio.com/shopfts/images/icons/resource824.htm] [automobile recalls] recalls ((http://favoritethingsstudio.com/shopfts/images/icons/resource824.htm automobile recalls)) [| automobile recalls] "automobile
recalls":http://favoritethingsstudio.com/shopfts/images/icons/resource824.htm [url|http://nicolamenicacci.com/board/wp-content/uploads/media/sitemap.html] [url] [3] ((http://nicolamenicacci.com/board/wp-content/uploads/media/sitemap.html url)) [| url] "url":http://nicolamenicacci.com/board/wp-content/uploads/media/sitemap.html tracc4tnon Next Page: Vaginal
tablet
Previous Page: Dental cones
Mouth Dissolved tablets/ Rapidly Dissolving tablets (10)
Known to the FDA as orally disintegrating tablets, they are also called mouth-dissolving, fast-dissolving, rapid-melt, porous, orodispersible, quick dissolving. These kinds of tablets are preferred when fast action or relief is desired. Most commonly used drugs under this formulation are the agents active against migraine. The tablets are designed to disintegrate as well as dissolve within one minute or some within 10 seconds of oral administration in limited quantity of saliva. They liquefy on tongue and patient swallows the liquid, without the need of water. A number of techniques are used to prepare these tablets, including lyophilization, soft direct compression. Matrices having an API and high porosity are also being prepared using sublimation process. Urea, urethane, ammonium carbonate, ammonium bicarbonate, hexamethylene, benzoic acid, naphthalene and camphor are commonly used for sublimation processing as they they volatize rapidly. After removal by sublimation, these inert volatile substances leave the matrices with a high porosity. Disintegrants and sugar based excipients, such as sodium starch glycolate, cross carmellose sodium, mannitol, xylitol, dextrose, fructose, maltose and polydextrose have been incorporated in almost all the orally disintegrating dosage forms (ODDFs). Loading of drug is made by preparing a blank and drug is post loaded. Generally the drug in solution is added after which the solvent evaporates. Taste masking poses numerous challenges since the drug product dissolves in mouth, any taste of drug must be covered, either by flavoring technique or by micro encapsulation or nanoencapsulation. A major drawback of most of these systems is that the packaging system needs a higher degree of protection due to the lower hardness and more friability of the porous nature of tablets, except the DuraSolv technology of CIMA Labs, which are suitable for rigors of bulk bottle packaging. Keep the orally disintegrating tablet in the blister pack inside the outer foil pouch until the patient is ready to take the medicine. Make sure that operatorâÃÂÃÂs hands are dry and peel open the blister to remove the tablet. Place the tablet on tongue and let it dissolve. These dosage forms have become a delivery system of choice for most patients as they provide comfort for administration throughout the day. Pharmaceutical companies, on the other hand, benefit from value addition in terms of product life-cycle management in todayâÃÂÃÂs market.
Next Page: Vaginal tablet
Previous Page: Dental cones
Retrieved from "http://www.pharmpedia.com/Tablets_used_in_the_oral_cavity:Mouth_dissolved_tablet"
This page has been accessed 779 times. This page was last modified 22:55, 18 August 2008. All content, except where otherwise noted, is licensed under a Creative Commons Attribution License.
